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Prepare to be downvoted to oblivion. HN is a leftist echo chamber. If you question vaccines, climate change, systemic racism, or the trans ideology, your voice will not be heard.

I’m probably shadow banned already.


You said it better than I could have. Amazing how no one will consider how overstimulating the immune system might create autoimmune disorders.


Have you not noticed the complete disregard the United States has for its citizens?


And some people still vote republican, despite a consistently worse record on caring for citizens.


The republicans aren't perfect, but they're more effectively hamstringing the government than anyone else.


What you said is equivalent to "they are more effective at making themselves useless". I can't disagree with you, but I think Americans deserve a useful and competent government.


When you give people enough extra money to buy elections that's what they do.


Don’t people still talk about “low seratonin levels?” I always found it suspect that we say someone’s levels are low without actually measuring them.


Yes, and psychiatrists never believed it was "low serotonin" at all, or at least claim to have never believed it.

For ADHD, stimulants actually do treat it by fixing "low dopamine"… in specific areas of the brain. But "low dopamine" is also a description of Parkinson's disease.

But SSRIs don't work like stimulants do; they take a lot more than half an hour to take effect. We don't actually know how SSRIs work in the people where they do work.


> But SSRIs don't work like stimulants do; they take a lot more than half an hour to take effect.

Sorry, need to be an anecdote for you. Prozac makes me manic in about 5 hours. We know how SSRIs work, the problem is they are treating a symptom not the cause of depression which is immune dysfunction.

If SSRIs did not increase serotonin there would be no risk of them causing serotonin syndrome, and they do.


> the problem is they are treating a symptom not the cause of depression which is immune dysfunction.

Yeaaaaa that's gonna be a serious "citations (plural and trustworthy) needed" from me there



"The role of immune dysfunction in BD is currently unclear, with low-grade chronic inflammation (increased plasma cytokines, soluble cytokine receptors, chemokines, acute phase reactants) and T-cell activation features that may be associated with BD, but the results are controversial"

If this is your best citation, then I don't know why you expect everyone to know about and be confident in this theory. And that's without even questioning whether bipolar and depression are the same thing.

Your search results are all over the place and don't show anything coherent.


Sorry, wrong link.

https://www.cell.com/neuron/pdf/S0896-6273(20)30431-1.pdf

“It is now well established that dysregu- lation of both the innate and adaptive immune systems occur in depressed patients and hinder favorable prognosis, including antidepressant responses.”


That sounds like evidence it's an important factor in treatment, but it doesn't mean we can be confident it's the cause.


The fact we still called them SSRIs is the part that gets me. But I suppose until we know how they actually work we can’t just call them “thingy”.


They're called SSRIs because pharmacodynamically, that is what they do. Not sure what's so wrong with that.


They Inhibit the Reuptake of Seratonin Selectively. What should we call them?


If they do something else as a side effect, but it turns out that's the main effect, it might be worth renaming them.


Most brain-altering drugs have effects beyond just the main target. See this chart for an NDRI: https://en.wikipedia.org/wiki/Bupropion#Pharmacodynamics


I discovered that Midjourney can’t generate a question mark, and if you use the /describe command and give it a picture of a question mark, it hallucinates.


My favourite Midjourney weirdness is what happens if you try to get it to draw you a "horseshoe" (or "horse shoe" - try both).


for those of us in the peanut gallery... what happens?



That's hilarious! Some of them look like they're trying to create those images on google search where it's a "horse shoe" logo of sorts.


Like my comment on question marks, horseshoes are even easier to generate. Check the gallery site and it's full of completely normal ones.


Saying "check the gallery site" would be a lot more useful if you'd link to examples in the gallery site.

https://www.midjourney.com/app/search/?search=horse%20shoes has some - most of them are weird, but a few are OK, like this one:

https://www.midjourney.com/app/search/?jobId=7ba6779d-8fde-4...


"horse shoes" is different than "horseshoe" and will give you different results.

I didn't feel like linking a search was useful as only people who had memberships could use and see it, and you were able to do it yourself as shown.


Oh fair enough! I didn't realize the search feature only worked for paying users. TIL.


I tried today for it to draw a horse with pink shoes (or sneakers). Could not do it.


midjourney, and I suspect all image generators, can’t imagine scenes without a floor.

Ask it to draw -a solar system.

- A planet floating in space

- A floating city

It has to have an in-image observer, who stands on the ground.

It also fails with images that display extreme perspective.

- A mountain that pierces the sky.

- A space elevator.


Huh. We seem to be having very different experiences.

- A floating city[1]

- A planet floating in space[2]

- A space elevator[3]

[1] https://cdn.discordapp.com/attachments/1003683981184737422/1...

[2] https://cdn.discordapp.com/attachments/1003683981184737422/1...

[3] https://cdn.discordapp.com/attachments/1003683981184737422/1...


Nice. It looks like there are still similar issues, but some things have improved.

I went through my results to check:

1) Floating city came out much better than my results a month ago.

- Prompt: Flying city - https://cdn.midjourney.com/85e254c4-d782-47a5-b63b-db8d20e54...

- Prompt: Flying city in space - https://cdn.midjourney.com/d8b9a582-6056-4fec-a0f2-e939c203a...

2) Planets was 50/50. the top 2 are prime examples of the floor issue.

- Prompt: A planet surrounded by the emptiness of space — https://cdn.midjourney.com/35246b1f-b344-4015-972b-512b770c3...

3)Space elevator, The first image is quite good

- prompt: Science fiction space elevator vanishing point in the sky - https://cdn.midjourney.com/0a92bbcf-329a-480d-a0eb-aec368eb7...

Vanishing points/ perspective dont seem to be grasped, leaving images constrained to certain view distances from observer as well as viewing angles. (I am not sure if those are the correct technical terms to describe the problem).

- How do solar systems work for you?

Prompt: solar system in space. https://cdn.midjourney.com/3873cdc1-fa9f-4a54-b5d5-c2336aa08...


the hallucinations is exactly what I enjoy the most about midjourney. If you want a detailed photo of exactly your prompt, I'd probably not use midjourney, but for making weird wonky artistic stuff, it's amazing. Trying to make anything actually visually appealing and artistic with Dall-E and the rest is a pain in the ass.


It definitely can, I see a bunch of great examples on the gallery site just by searching up "question mark".


I tried other punctuation marks and MJ can't do them either.

Exclamation mark generaties all kinds of vertical objects, comma results in a generic pretty face, and semicolon is ...weird.


Australia became a full on prison colony. They didn’t contain covid, they imprisoned their entire population.


I understand why you believe that. Plenty of other Australians think likewise (including most of my Australian friends who live overseas).

And yet, in my home state of Victoria, the state premier behind the lockdowns was reelected after covid with a huge majority. It seems like the way the story unfolded for people inside of Victoria was very different to how the story was told everywhere else.


I am trapped inside of Victoria, unfortunately. I wholeheartedly agree with GP poster. We saw visitor bans, curfews, work permits, arrests, rubber bullets and riot gear police deployed as "epidemiological" measures. My respect for police and public service in general went right out the door. Now there is only fear. Biggest regret of my life to settle down here. The huge majority electing the same person only solidifies my view that they may just be the different biological species. The "premier" spared no expense in making the event all about him and only him - just check the Wikipedia page [0].

That's a feat no other leader in any world's jurisdiction even attempted to. I don't know if it is another "red shirts" undertaking or a sycophantic "grass roots" movement - wouldn't be surprised with both, but just don't care at the moment. Seeking an exit of Victoria, but the most likely one for me will be out of existence.

If you think public support validates the "measures", check another example of similar landslide victory - election in Belarus of 1994. That win was as democratic as they get, I am telling you as a first-hand witness. The support was very genuine, for at least a decade to come. As for myself and my family - we feel that we escaped that hellhole only to land in a worse one... where there is no escape from.

0 - https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Victoria


And someone who is free can choose to be as cautious as they please. They just can’t force their choices on everyone else.


I’m not sure I understand - are you arguing that universal healthcare is having a choice forced on you?


Losses are not fully tax deductible.


Fair enough. It's fully deductible when used to offset capital gains as far as I know.

To offset regular income, it's only $3000 a year but losses can be carried forward (though it stays at the dollar value, no inflation is taken into account).

So often largely deductible with some caveats.

It still seems asinine that bad investments are essentially tax subsidized, but whatever.


“What happens once will never happen again. What happens twice will surely happen a third time.”


This looks like it’s purely about gaming signup metrics for Threads. Make it easy to try, create a huge disincentive to cancel, and suddenly you have a wildly successful, “sticky” app.


Next step "due to incredibly good reception, we are auto-creating a Thread account for anyone signed up in any of our other platforms - saving our users billions of minutes!".


Well it seems extremely unlikely to be an oversite I’ll admit. ;)


Similar to the strategy for Google+ back in the day. It didn't work back then, big chances are it won't work now, either.


Google+ was a product trying to break into a market where the market didn't really need another product. Threads is obviously looking to take up the mantle for where Twitter is dying, and people are actively looking for a Twitter replacement. So comparing Threads to G+ is just not a good comparison.


I read a horror story on Slashdot about a user losing their Gmail account because of some issue on Google+ and that was it for me. I stayed away. My email account was too precious to risk.


my OpenAI API account got nuked due to a missing organization error when I switched clients one night. I just got an email back from their support... took them 2 months. For reference, ChatGPT API has been out for only 3 months.


Threads is being bootstrapped off an existing billion user social network and completely aligns to Meta's core values and business model.

It's pretty much the complete opposite of Google+.


I'm saying that FB wouldn't have needed to resort to this lousy strategy if that "alignment" that you mention would have given them enough numbers all by itself.

As such, adding a dying social-media activity ("short" texting) to a fading social-media property (IG) is also less than ideal for Meta the company.


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