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By "back Illinois bill", does that mean they wrote it?

So the "checks and balances" we were taught in school was just nonsense?


How could it be that a political system which remained largely structurally unchanged since the freaking 18th century isn't equipped to deal with everything that has been going on in the world since then?

It must be due to bad actors.


Kinda yeah, much like how Americans are taught that they are a bastion of democracy, yet your convoluted electoral system has led to multiple instances of your president losing the popular vote.


They weren't nonsense until we had people in positions of power decide that they were.

At the end of the day, pieces of paper are just pieces of paper.


... and we seem to be unable to make something that works without "turning it off and turning it on again" :-)


Forth does not specify threaded code. Implementation is left to the implementor.

Internally Forth can be direct threaded code, indirect threaded code, byte code, sub-routine calls or optimized native code.


The 16K memory block is connect to the TMS9918 video chip and is accessed by port read/write. The TI-99 out of the box only has 256 bytes of RAM memory on the 16 bit buss.

UNIX99 uses an after market card with 1Mbyte of RAM on an 8bit external buss used for peripherals. This card replaces the old 32K RAM card made by TI in the 1980s.


Sure. But the emitted chemicals strengthen/weaken specific neurons in our neural nets. If there were analogous electronic nets in the bot, with analogous electrical/data stimulii, wouldn't the bot "feel" like it had emotions?

Not saying it's like that now, but it should be possible to "emulate" emotions. ?? Our nets seem to believe we have emotions. :-)


Probably worth mentioning that writing a big project in Forth is more like creating an OOP framework.(if you are disciplined)

The end result of that is one doesn't write the program in "Forth" per se but in the domain specific language you create for the job. This is how Forth gets more productive than pure assembly language if the team documents things well and follows the prescribed system.


Forth is a compiler but what it "compiles" is not standard. The implementor decides what they need. Forth can compile pointers to native code that are the VM's instructions, called direct threading. Forth can compile pointers to pointers to native code VM instructions, called indirect threading. Forth can compile byte code like OpenFirmware/OpenBoot.

And modern systems compile optimized native code (VFX Forth, SwiftForth) but still remain fully interactive at the console.


We have one solid example of cancer caused by members of the HPV family. The disease can be transmitted via body fluids and/or contact. So there's that.

My laymans take: Cancer is a disease of the DNA of a cell. Viruses survive by altering cellular DNA. It begs the question: How many other viruses cause cancer?

It also seems clear to me that the virus may not be the sole cause since not everybody gets cancer so it is a multi-variable problem.

Virus + X = cancer

This will be harder to nail down but with modern data tools we should be able to get there.

Makes me wonder: Is the cancer "industry" searching for causes or just after-the-fact treatment?


Makes me wonder: Is the cancer "industry" searching for causes or just after-the-fact treatment?

Why brag that you are uninformed?

Some of the more successful interventions for cancer are preventative (for example removing polyps during colonoscopies) and genetic counseling is common.


There are other examples of oncoviruses including: Epstein-Barr virus and Human herpes virus 8 (Kaposi's Sarcoma).

Makes me wonder: Is the cancer "industry" searching for causes or just after-the-fact treatment?

There are billions of dollars spent on this problem through huge DNA/RNA/Epigenomics/Chromatin Accessibility sequencing initiatives. There is also a huge amount of model system work such as mouse models.


That is super news. Thanks for this.


Viruses are just another "mutagen". No different from UV causing DNA damage in your skin cells, other than the mechanism in which it occurs. The cause for cancer is well-known and, in hindisght, obvious, which is mutation.

The challenge though is mutations can happen in a plethora of ways and their effect is highly dependent on which gene is mutated. There is also the tissue context, e.g. inflammation, spatial structure, etc., that can setup a background for increased mutation. That is why targeted therapies are often the most effective, because they target the general causative feature of a given tumour subtype, the problem is not every protein can be targeted now and each tumour, even within the same subtype has their own unique mutational profile due to the stochasticity of the way mutations occur over repeated rounds of cell division.

And back to viruses, yes they cause cancer because they can mutate DNA. But it's pretty clear, most of the viral "enriched" cancer types are generally in places where transmission is commonplace, e.g. reproductive organs or head/neck.


Apparently, mitochondria and their (non-repairable) DNA play a big role as well.


Why stop there? Perhaps we must recurse our conspiracy theories one level more: what if the faction of the cancer industry that wants after the fact treatment is propagating theories like yours so that they can make the cancer industry seem like all frauds and stop research until proven otherwise. Then they’ll be able to sell their current methods even longer.

Hmm, a disturbing and dangerous thought. But what does that mean for my comment? Who is paying me? What do they want? Will the lizard men of Hippocrates command the subtle ghasts of Papilla to inflict deep and lasting injury to our very souls?

Troubling. We must investigate.


People who need to hit their revenue numbers make allocations decisions. That's not a conspiracy. It's what people have to do to keep their jobs in industry. And those decisions affect what gets the resources.

And yes I know that outcomes after detection have improved, but the HPV vaccine shows an alternative that to me deserves more resources.

I am simply frustrated by 60 years of research and lots of dead friends and family. If that's a crime get the tar and feathers while I strip down to my shorts.


Bullshitting online while being frustrated is not a crime. We all do it. I’m just calling it that - which we should also all do.


An engineer at RCA in New Jersey told me that at the first(early) NTSC color demo the interference was corrected by hand tweaking the color sub-carrier oscillator from which vertical and horizontal intervals were derived and the final result was what we got.

The interference was caused when the spectrum of the color sub-carrier over-lapped the spectrum of the horizontal interval in the broadcast signal. Tweaking the frequencies allowed the two spectra to interleave in the frequency domain.


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