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Change my mind:

Being active and getting outside are associated with a multitude of health benefits and is correlated with vitamin D level. The Vitamin D Council pushes vitamin D supplementation based on this research (and funds it?) but there is minimal methodologically rigorous research showing health benefits from exogenous supplementation.


The person interviewed in the BBC article is a football player and fits the bill of 'active' and 'gets outside', none of which addressed the underlying issue.

My read on this article, which is validated by all the comments in this thread, is that it's a PSA to public health officials to have better outreach for darker skinned individuals living in the UK who seem to be getting systematically misdiagnosed because of a lack of knowledge.

> there is minimal methodologically rigorous research showing health benefits from exogenous supplementation.

In this day and age, this shouldn't be an open question tbh. There is an extensive body of research, with dozens of meta-analysis / systematic reviews aiming to settle the score on this. If you let Claude or your favorite LLM du jour loose on Pubmed I'm sure it will surface some very reliable conclusions.


> In this day and age, this shouldn't be an open question tbh.

Are you being paid by the Vitamin D council or something? I thought HN was about curious conversation.

> There is an extensive body of research, with dozens of meta-analysis / systematic reviews aiming to settle the score on this. If you let Claude or your favorite LLM du jour loose on Pubmed I'm sure it will surface some very reliable conclusions.

After I finished my degree in human nutrition, I decided to go to medical school because of the amount of free time I was spending on PubMed. I previously had high hopes for vitamin D, but I am now a skeptic specifically due to the dearth of rigorous and supportive studies on PubMed.

Do you have any favorite trials of exogenous supplementation that are in humans, large sample size, RTC with appropriate blinding, and have positive, meaningful / non-surrogate outcomes? This would seem easy to accomplish given its wide availability, low cost, and excellent safety margin.


> who seem to be getting systematically misdiagnosed because of a lack of knowledge

In contrast, vitamin D testing seems to be fairly commonplace in my practice setting, and unfortunately I see it being used as a scapegoat for dubious symptoms routinely.


Did nobody read the article?

> While her symptoms are not directly linked to vitamin D deficiency


Because they did not, that's ridiculous. Just correlation. Their symptoms sound very similar to vasovagal syncope, which is a fairly regular occurrence in young healthy people that perhaps skip breakfast and then get their blood drawn / experience nausea / many other causes. They generally recover fine with no intervention other than some rest and getting a meal.

The article even says explicitly:

> While her symptoms are not directly linked to vitamin D deficiency


I've been really hoping to get Whisper running on a coral, but it can't even do that. There was recently some progress getting it to export to tflite (and even an official example added) but the coral is missing some instructions.

Can you elaborate?

I don't understand why you would need Tailscale, for example -- shouldn't your VPS have a static address to which you can reach out from your home and also connect remotely, making Tailscale superfluous?


- They're not using a VPS, they're using a server hosted inside their house

- Lots of ISPs use CGNAT which means you can't always have direct access, especially on mobile. Tailscale solves that via DERP (https://tailscale.com/docs/reference/derp-servers)

- Static public IP addresses for ingress cost money from the cloud provider, they're not cheap either

- Having a public IP makes the ports open to attackers, using Tailscale the attacker has to hack your tailnet before they can hack your server

- You have to buy a DNS name for your public IP, you don't need one if you use Tailscale thanks to MagicDNS

- Tailscale has a bunch of nice features like Let's Encrypt integration, OAuth support, Tailscale SSH, etc. that make the experience quite nice overall


> You have to buy a DNS name for your public IP

What are you talking about?


If you want TLS for your websites/webapps you're gonna need a DNS name to get a cert


No, Let’s Encrypt provides IP address certificates for free.


Interesting, apparently they added that as a feature a few months ago.

https://letsencrypt.org/2026/01/15/6day-and-ip-general-avail...


I use the VPS mainly to route traffic from my in-house server.

I am sure there is a way to avoid tailscale, but I like putting it on everything I can. It is pretty easy to use.


You can find instructions for making and soldering on a small antenna to the common "mini" dev board that reportedly helps quite a bit


Agreed -- not my wheelhouse, but couldn't you just build rust earlier in your process using LLD, then build mold, then build everything else?

Would that meant that building rust is slower, but everything else is the same, and you don't have to maintain a fork of another complex project?


Rust requires python and perl and musl and openssl and 80% of the entire wall time of building the whole tree.

Rust is the single most expensive thing to bootstrap in any given linux distro.

It is the thing you need mold the most for to speed things up.


Hopefully, someone can do some work on decreasing the requirements needed to build rust itself and ease bootstrapping.


I sure hope so. Go is the gold standard to copy here, which is not surprising given the involvement of Ken Thompson who authored Reflections on Trusting Trust.

Unfortunately Rust does not even do full source bootstrapped deterministic builds themselves. Their release strategy is entirely the honor system, where everyone trusts their pinky swear that a single computer or person will never be compromised and allow for the injection of malware into the binaries everyone downloads from rustup.

The only reason we have even the crazy long bootstrap path we have today at all is the hard work of mutabah, an individual independent hacker that does it as a hobby.

The rust team seemingly considers memory safety as the only security problem that matters, and supply chain attacks out of scope.


Along these same lines, it seems to me that patients in the US can rarely afford the exorbitant and escalating cost of medical care, so with increasing frequency they expend considerable effort trying to identify any possible error that they think could get them a break on their bill or enough of a legal case to give them a fighting shot at beating medical bankruptcy.

I have personal knowledge ofcases with acknowledged errors and apologies that have also resulted in the hospital eating the full cost of care.


> I have personal knowledge ofcases with acknowledged errors and apologies that have also resulted in the hospital eating the full cost of care.

+1 of providers eating the cost of care due to insurance misfilings (e.g. failure to secure prior auth when the patient's plan required it, which for-profit plans are increasingly using as a disingenuous bullshit way to legally and effectively limit payouts for care that should be covered)


> there is quite literally no good evidence that boosters for Covid do anything for otherwise healthy people who have already been infected

Before I dive back into the literature, as you claim to be stating this in good faith... is the "good" load-bearing here? Relentlessly attacking methodology is an easy way to make this kind of general claim.

Also, are you talking narrowly about a group of people that has had COVID but never had a prior COVID vaccination? (In which case is it still a "booster"?) Or is a proper steelman of your position that anyone that has had COVID, regardless of prior vaccinations exposure, does not benefit from additional vaccination in any meaningful sense?


Is it load-bearing, or is it the seam?


NAC is now a pretty common intervention for alc hep -- by definition post drinking -- so I would bet the mice data doesn't translate.


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