> Do we have the numbers yet on the effects of vaping all day every day on cardiovascular health and lung cancer?
Even when we don't have the numbers for everyday long-term use we already know the chemical and biological mechanisms that make smoking so harmful and carcinogen and we can measure that these substances are almost entirely absent in vapor during normal use of a vape because almost all of the problems with smoking come from burning tabacco and inhaling the fumes and vaping is simply way cooler and there is no fume but vapor (hence the name) and we know that the potential of vapor to do harm is way lower than fume. We never have any long-term data for anything new. But to make an argument for not consuming something you would at least have some reasonable mechanism through which it could be harmful and a lot of those known to be harmful mechanisms are present when smoking but absent when vaping. Even the British National Health Service agrees that vaping is at least 95% less harmful than smoking and this is a reasonable position.
> Trading the terrible effects of burning tobacco versus the insane amount of nicotine from vaping seems like an unknown tradeoff to me
This is just black rhetoric that is not evidence-based. How do you know the amount of nicotine is "insane" during normal use?
All available evidence points to vaping being at least one magnitude less harmful than smoking and this is backed by what we know about chemical and biological processes of the chemicals involved and through medical reports about people who replaced smoking with vaping. It would be irresponsible to deny smokers who can't quit a way to harm reduction just by claiming we don't have any long-term data. We know enough about combustion, vapor and the chemical and biological implications to be quite confident that vaping is much less harmful than smoking.
That doesn't mean we should promote it to anybody who is not already a smoker. But as a means to reduce harm for someone who seems unable to quit smoking it should be considered.
I think you read my comments as some self assured statement or argument whereas I was genuinely asking questions.
I dont doubt given an equal amount of vaping to equal amount of smoking, vaping is far healthier. But to what end? Is smoking 1 cigarette a day worse than vaping 2-3ml of 50mg/ml nicotine? How about 3-4?
As far as I know the academic consensus is that taking in more nicotine, even a lot more, doesn't turn vaping into something as harmful as smoking. Addiction is the main established "harm". Nicotine, even very much of it, is not considered a carcinogen. There are studies that suggest it could promote tumour growth but it hasn't been shown in humans. There is also decades of data from nicotine replacement therapy and Swedish snus users and it shows little to no increase in heart attacks or strokes in otherwise healthy people. Another risk is accute poisoning, i.e. swallowing large quantities of liquid by children. As far as I know even the more alarming voices regarding nicotine do not regard it as harmful as inhaling fumes from combustion.
Also I don't think that there are many people that overdose nicotine regularily because it causes nausea and dizziness so people are normally self-regulating the nicotine dose automatically. So the scenario you are proposing doesn't seem to be something we can actually observe as a common consumption pattern.
Too much nicotine is far closer to drinking too much coffee than to smoking and has similar acute effects which is why almost nobody does it on a regular basis.
It's not really the nicotine that causes the obvious damage though. Studies have shown that the vape smoke stimulates the vagus nerve which causes changes in the cardiovascular system that could likely cause heart disease
On top of that it’s obvious that what goes into the lungs generally stays in the lungs, and vapes are full of all sorts of weird flavours and e numbers
But the truth is even if you were vaping water all day it would likely still damage your cardiovascular system
> Studies have shown that the vape smoke stimulates the vagus nerve which causes changes in the cardiovascular system that could likely cause heart disease
Can you name this study? Are you talking about "E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice"? This study did not find what you claim. All it found is that in mice the heart rhythm during and right after exposure increased. This is far from claiming that it "could likely cause heart disease" in humans. Also human switching studies point the other way. smokers who move to vaping show improvements in blood vessel function within weeks. I don't know why people really need to twist study results to depict vaping more harmful than it is. Yes, it is not healthy and you shouldn't do it. But all scientific evidence conclusively points to vaping, even heavy vaping, still being way less harmful than smoking because we already know that basically all harm comes from inhaling the residues of combustion, not from the nicotine. Condeming vaping as being equally bad as smoking is irresponsible and unscientific and prevents proven harm reduction for heavy smokers.
> Condeming vaping as being equally bad as smoking is irresponsible and unscientific and prevents proven harm reduction for heavy smokers.
I never said this did I.
Also you’re talking about smokers moving to vaping, whereas at the moment plenty of people are going straight to vaping due to people over arguing how harmless it is compared to smoking.
That's about as correct as saying cyber security is largely solved by referring to a "benchmark" that a particular virus scanner is able to detect and prevent infection with 720 known computer viruses. All this shows is that the model has been fitted to the benchmark, not that it is hardened against any conceivable way of prompt injection.
And regarding vibe-coding a mobile app with zero users, probably zero monitoring and zero everything like all the other vibe-coded apps that have zero users. Sure you can do that but what is the point?
Well, in case of a bank it can. And it happens on a daily basis. In fact thats how most private bank money enters the system in the first place either when a bank makes a loan or when it buys any other asset like e.g. a corporate bond (you can conceptualize a loan as an asset purchase as well, the bank buys a promise to pay from the borrower which is recorded as an asset of the bank). Both are a balance sheet extension from a double-entry bookkeeping point of view.
The 4 operations double-entry bookkeeping allows are:
1. balance sheet extension (e.g. making a loan)
2. balance sheet reduction (e.g. loan repayment)
3. asset swap (e.g. a bank buying a government bond with central bank reserves)
4. liability swap (e.g. transferring money from one account to another)
So it may be more accurate to just say that every event that affects the balance sheet must be one of those 4 operations.
Also see "Money creation in the modern economy" - Bank of England Quarterly Bulletin 2014 Q1
> Well, in case of a bank it can. And it happens on a daily basis.
You mean it happens when a bank borrows money from a central bank, right?
Not every balance sheet expansion constitutes the creation of money, e.g. when you put money on your bank account, the bank's balance sheet grows, but the money is not newly created.
> You mean it happens when a bank borrows money from a central bank, right?
No I mean in the moment the bank grants a loan. The money the borrower receives is new money, its not taken from anywhere else. But at the same time the bank records the credit as an asset which makes it a balance sheet extension.
> when you put money on your bank account, the bank's balance sheet grows
That's true, you hand over cash to the bank which becomes its asset and your account balance is marked up for the same amount. Not all money in circulation is accounted on a bank balance sheet, but most of it is bank deposits. cash is an exception, it's public money, not private bank money. When you "put money in a bank account", i.e. you bring cash to the bank you are essentially selling your public government money to the bank and it pays you with its own private bank money (which it "creates" as well).
But this is only a micro-view of a single event. In the aggregate money is created when either the government runs a deficit or when banks make loans and money is destroyed when taxes are paid or loans are repaid.
Well, that's not money created out of nowhere. The balance sheet extension creates money and an equivalent liability. That's the point of the statement, not money supply and its regulation.
Fair enough, just wanted to point out that banks originate money as part of the lending process. You could maybe call that "money out of asset purchases" whatever that means and yes its a valid balance sheet operation. I guess you would agree that a bank needs no prior savings or deposits in order to make a loan, i.e. it doesn't need to have money that it "lends out"?
Or let me ask you this: What would in your opinion be a valid example of "money out of nowhere"?
some engineers and average person sees the entire fiat money as something that needs to be "earn" or get returns from investments only. they dont see how it's literally created as free and out of nothing.
Very true but also understandable because that's how most households perceive it from their micro-economic standpoint. But its very deceptive because it suffers from a fallacy of composition. If households want to earn more than they spend (i.e. save), some other entity must spend more than they earn. This can be somebody taking a mortgage or the government running a deficit. Debt and savings are mirror images of the same thing, two sides of the same coin and we use double-entry book keeping to track them.
It is very insightful to view money as a creature of accounting for debtor-creditor relations rather than thinking of it as some kind of commodity.
Gold never really served as a currency, rather as collateral. If gold is a currency than any marketable asset is. A good definition of "currency" or "money" would be one that distinguishes its characteristics from commodities and the only useful one I know of is the "credit theory of money". Money is a promissory note, an accounting device and that is true for at least 5000 years of monetary history tracking it back all the way to ancient babylonia. Throughout that history money has taken many forms reaching from clay tablets, metal coins, tally sticks, paper money all the way to digital currency but all those share a common principle which is that they are all records of indebtness, promises to pay. Barter is not and has never been the default mode of commerce at all or a anthropologist Caroline Humphrey put it:
“no example of a barter economy, pure and simple, has ever been
described… all available ethnography suggests there has never been such a thing”.
Barter as a form of commerce pre-dating monetary economies is a myth, a post-hoc rationalization of how money might have came about from the perspective of somebody that already lives in a monetary economy and it's entirely an armchair theory that does not rest on any historical and anthropological evidence.
What is true is that between parties that do not have an established relationship barter occurred and it is true that people seek to hold assets and demand tradable collateral during periods of unrest. But barter has never been a primary way to do commerce between parties that had a long-standing relationship. A theory of credit-money is way more useful to explain real world behavor than a metalist approach is. Gold isn't used in daily transactions, it primarily sits in basements and is also is not an input to allmost all of production. What makes us rich in real terms is not gold but knowledge, machines and technology.
While that might be true there is still a point to be considered regarding vaping which is that it is an order of magnitute less harmful than smoking tabacco cigarettes because nothing is burned in a vape and the "burning stuff" is what makes normal smoking so harmful. Therefore I'd argue it should definitely be available for smokers at a price tag lower than cigarettes if they can't quit smoking to reduce harm. This would massively decrease the huge costs for health care.
That's correct, in normal use the coil (the term used for the metal) never glows, it's not even close to glow. This is because it is surrounded by cotton soaked in the liquid which always cools the coil and which produces the desired vapor. If the coil would ever start to glow this is called a "dry hit" and it usually happens if you failed to monitor there's enough liquid in the tank. In this case the cotton immediately starts to burn and believe me inhaling that is disgusting and you would immediately stop. In fact you even stop before that because if the cotton gets dry it stops tasting any good.
Vaping is (compared to actually smoking tabacco) definitely harm reduction and significantly less harmful (which doesn't mean its healthy and you should do it). Yet it is treated like smoking cigarettes by law. For example in Germany you have to pay tabacco tax on the base liquid (which doesn't even contain nicotine) if it is intended to be used in a vape (17 cents per milliliter) which increased the price of the base liquid from around 10€ to 170€. But the base liquid only consists of two things (propylene glycol and glycerol) and both those substances you can by cheaply in a vet doctors online shop for maybe 5€ each liter. It's ridiculous.
When i made my own i could make 500-700ml for $20. The expense is all up-front if you don't know what flavors you want or you want to experiment with recipes - the flavoring is relatively expensive if you want a lot of variety. If you're a "cherry cola" or "golden tobacco" sort, then the up front cost is about $40 (or was, 6 years ago), and you can make over a gallon of liquid at a strength of ~2.5% (25mg/l) off a single purchase of everything. you need 2 liters of PG, 1 liter of VG, and 1 liter of 100ml/l nicotine. then your flavoring.
anyhow, i buy juice now, too, but mine was better. I never used sweeteners. My current go-to is Naked Euro Gold 12mg, but i am on the hunt for a 25ml nicotine salt version of a similar flavor. (nicotine salt vs freebase nicotine, salt is more "mellow" and lets you put a higher concentration in, which translates directly to less use, as you're satiated much faster.)
I also feel like this really is one of the biggest pain points when writing single page apps. There is no good standard and everybody is promoting his/her way to do it that works well in a TODO app example but kinda fails in a big production application.
I don't like that concept of essentially inlining styles in the class attribute. It is just a misuse of html classes.
Class names should be used sparingly and describe the semantics of an element rather than its visual appearance. It should be something like class="button submit disabled" instead of class="f6 link dim br1 ph3 pv2 mb2 dib white bg-black".
If anything these styles should be exposed as sass mix-ins that you can use in your own styles. So you have a named set of style mix-ins that do not pollute class names.
button is a tag, submit and disabled are tag attributes -- surely you don't need these classes, they're either superfluous or you're not doing semantic HTML.
I agree that you could in a lot of cases get along without these classes. But sometimes you want e.g. an anchor acting as a button in a web application. Or you want a button element with browser styles. You could argue that this is also already an anti-pattern but it does way less harm then leaking inline styles into the namespace and it is still semantic. Also this was just an example (maybe not the best one) to illustrate my point that class names should be semantic and not express solely presentational attributes. The later is what styles are there for.
Especially in a javascript driven web application you may want to select all "buttons that are disabled". But you never want to select elements that "have a rounded border of 2 px and a grey background and italic font style and....". This takes class names ad absurdum.
does the last example if you classed that style, doesn't it? I've only done a little CSS, not very recent ... unless you're recruiting, then I'm an expert ;o).
I imagine though there are times when you want to class (some) button tags as .button.
I feel exactly the opposite is the case. Hooks can improve expressiveness a lot by helping developers to separate concerns and keeping logic that belongs together in a separate place.
While I understand the argument that hooks encourage to make dumb components stateful this is already the case with class based components. At the end of the day a developer is responsible for separating concerns of his application and he can fail to do so with class based components and hooks the same way.
Even when we don't have the numbers for everyday long-term use we already know the chemical and biological mechanisms that make smoking so harmful and carcinogen and we can measure that these substances are almost entirely absent in vapor during normal use of a vape because almost all of the problems with smoking come from burning tabacco and inhaling the fumes and vaping is simply way cooler and there is no fume but vapor (hence the name) and we know that the potential of vapor to do harm is way lower than fume. We never have any long-term data for anything new. But to make an argument for not consuming something you would at least have some reasonable mechanism through which it could be harmful and a lot of those known to be harmful mechanisms are present when smoking but absent when vaping. Even the British National Health Service agrees that vaping is at least 95% less harmful than smoking and this is a reasonable position.
> Trading the terrible effects of burning tobacco versus the insane amount of nicotine from vaping seems like an unknown tradeoff to me
This is just black rhetoric that is not evidence-based. How do you know the amount of nicotine is "insane" during normal use?
All available evidence points to vaping being at least one magnitude less harmful than smoking and this is backed by what we know about chemical and biological processes of the chemicals involved and through medical reports about people who replaced smoking with vaping. It would be irresponsible to deny smokers who can't quit a way to harm reduction just by claiming we don't have any long-term data. We know enough about combustion, vapor and the chemical and biological implications to be quite confident that vaping is much less harmful than smoking.
That doesn't mean we should promote it to anybody who is not already a smoker. But as a means to reduce harm for someone who seems unable to quit smoking it should be considered.