Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

From my college years I remember that vaccination was hard because the outer shell of the virus is capable of mutating so rapidly that it's hard to make antibodies specific to it.


I am not an expert but I notice that we seem to manage variability with Influenza by creating a new vaccine every year.


The difference, as I (also not an expert) understand it is that HIV is unique in that it's so variable that the host never develops immunity to the disease. In most viruses, the immune system eventually develops an immunity and eliminates the disease. Influenza is an example of this; your immune system learns to fight off the strain that you get. The new vaccine every year is for the new strains.

The HIV vaccine mutates quickly enough that the host never develops immunity themselves, which makes triggering immunity with a vaccine very difficult.


There efficacy is debated though. Every other year you hear that the vaccine is not for the right strain of it.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: