A hotel being cleaned is a person you don't know entering your room every day and breathing all over everything. I'd much rather a single house where you can do a deep clean yourself on the day you move in and then be sure nobody except yourselves have entered the house until you've left.
Do you trust that the housekeeper who gets paid $15/hour and prob cleans 50 rooms a shift is really going to clean your place throughly? Also the amount of traffic in the hotel, the check-in counter, the people in the elevator, the room service food that has gone through multiple sets of hands....yeah sure this is safer.
I rather have an Airbnb that does remote check-in. Once there I will do my own cleaning and not worry about unknown traffic in my place for rest of the stay. In addition I can buy my own groceries therefore reducing another vector point of transmission.
Seems like a better proposition then the hotel IMHO if you really are scared of getting infected.
Personally in a hotel because I at least know that the hotel is going to be cleaned.