I would love to see zero barrier entry to creating a website (like twitter / name your favorite site that is not a static site) that can run on peoples laptops just by visiting a static javascript/html/css webpage. For this, you would need some decentralized backend storage solution akin to a sql or nosql database.

IPFS is not a database, perhaps one could be built on top but then who pins the data and who runs the gateway? IPFS gateways are particularly confounding at this juncture. Until IPFS gets native browser support for pinning and gateways it cannot be the storage layer for a decentralized database.

This kind of technology could help people take back the internet (imo) and webrtc goes a long way toward that goal. Even webrtc doesn't have the full promise of what I am suggesting however, it still requires a server that knows the IP of the other party so that you can directly connect (discovery). This would also need to be decentralized (somehow) perhaps only the discovery of peers would be done over a bootstrapped p2p DHT or something equivalent.