I use Bitwig Studio. It has that polished feel of Jetbrains products and has very good MIDI production tools among other things. Of course the downside it's not free and rather expensive, but it's linux native. All the VSTs that I need work through wine/yabridge flawlessly - Ample Guitars, Pianoteq. Even the crappy Kontakt works, but I don't use it much. Backend audio server is JACK2 with Pulseaudio sink.
Ardour is probably most popular DAW on linux and it's OSS/free, but I found Bitwig better for my use, mainly due to MIDI functionality.
Ardour is probably most popular DAW on linux and it's OSS/free, but I found Bitwig better for my use, mainly due to MIDI functionality.