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>I am pretty sure Sputnik V is fine. It has been administered to tens of millions inside Russia itself. If there were massive problems with it, we would know by now.

No, we wouldn't. Because most of the Vaccine AEFI tracking is based on voluntary reporting, and is known to only report around 1% of the events.

Even if it was not the case, we wouldn't still know without a control group. Basically this is why systematic trials are done to measure these things.

So this logic does not absolve Sputnik vaccine, or any other current vaccines in use.

https://www.nejm.org/doi/full/10.1056/NEJMp2033538



You are right. We do need systematic trials to confidently makes statements like the one I made. Thank you for pointing out the error in my logic.




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