Ketamine can be pretty rough on the bladder and kidneys. Please read up on the risks. It is definitely dangerous to take recreational doses several times per week - it seems that low/moderate doses every week or two avoids most of the problems while still providing therapeutic effects, but definitely keep an eye on the health of those systems, ideally with letting your doctor know so they can help.

Many of users on /r/researchchemicals using either ket or novel analogs at recreational doses regularly for both fun and depression relief end up with bladder issues after over-consuming for a period - so while it's a promising depression treatment, I'd recommend caution around dosage and frequency and titrating to find your minimum effective dose.