I took the Giving What We Can Pledge[1] and donate 10% of my income to effective charities for this reason. It barely makes a difference to me and it saves more than 1 life a year. They also have a really cool How Rich Am I calculator[2] to put it in context.

I still chose to pull the lever though because I don't have $18000 in my life savings yet.

[1]: https://www.givingwhatwecan.org/pledge

[2]: https://howrichami.givingwhatwecan.org/how-rich-am-i