> So does this somehow burn fat or does it just lower your appetite?

The article's subheadline is "A class of drugs that quash hunger".

> There are many others drugs that lower appetite

Not this well and/or not this safely.

There is only one class of drugs that lowers appetite outside of these GLP hormone drugs, those are stimulants like amphetamines. As someone on one of the GLP drugs for 3-4 months, and whose body tolerates it well, this is simply turning off the hunger switch. I will miss meals because I'm not hungry, since starting I have never felt "hangry" and I am satiated with small meals and do not feel hungry later. If I overeat, I will feel nauseous and sick.

I do not feel wired, foggy or feel like my personality or sleep cycle has been affected in the slightest.

There are others; https://en.wikipedia.org/wiki/Topiramate is one. Nowhere near as effective, though.

> There are many others drugs that lower appetite, and yet we still have an obesity crisis.

Which ones are prescribed in the US, on label, to treat obesity?

Doctors are reluctant to prescribe stimulants to their patients for various reasons. Also you don't keep the weight off with those.

You don't necessarily need a stimulant, you can also e.g. short the mitochondria using DNP. Doing so does have some fairly predictable downsides.

Ha! This made me think of DNP too-the rare drug that modifies the O of CICO. But you can't beat thermodynamics.