However, glucose can be stored and metabolised throughout the body whilst fructose requires processing in the liver. Our bodies are not designed to have a large instantaneous "hit" of fructose. They can cope with slow release of natural fructose in fruits, but in processed food it's soluble and released very quickly. The kinetics of how it's processed are very different.
Humans didn't eat a lot of sugar until fairly recently, too. And even if you did, you'd have to be very, very rich to be eating it 3 meals a day.
Now you can get sugary cereal for breakfast, sandwich bread with HFCS for your lunchtime sammo, and a curry jam packed with palm oil and sugar for dinner. And that doesn't count the cookies or Pepsi you slam in between.
Raw sugar of HFCS -- don't matter none, it's that you're slamming em at each meal, all the time.
