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They tested Ivermectin, Metaformin and Fluvoxamine, obviously everything's toxic at a high enough dose but are those drugs considered especially bad? It's not chemo, right?


As someone whose only previous knowledge of ivermectin was from being given it to treat a parasite infection acquired in the backwaters of southeast asia a decade ago, I've been confused to see it keep coming up in the context of COVID. I thought it was just some weird Internet fad from the pandemic, but then here's a Lancet article about a trial evaluating the use of it for "long COVID". What is the proposed mechanism of action?


For Long COVID there really is none, unless you think the virus sticks around somehow, and you also think Ivermectin works on the virus.


they're toxic at normal doses


What do you mean by that? If you take them too long/too many doses in a given year? I always thought they were reasonably safe.


well I mean diabetes patients have to take metformin and it of course prolongs their life but it also subjects them to potential lactic acidosis, because it's toxic.

Medicine is taking the lesser of two poisons because you literally don't have a choice in the matter. It can be way better than it is but we have such awful perverse incentives and lack of responsibility rampant in the field.


Sure, it's the risk of taking the drug vs the risk of not taking the drug. What about Fluvoxamine and Ivermectin though?




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