It's much easier to start in your home market, get experience there and then expand.
Also, the US is basically the best market for everything (fortunately or unfortunately), so even if you start in Latvia, the next market you enter will probably be the US.
This is because it's relatively open and has lots of people speaking a common language, with a (mostly) common regulatory system so you can spread the setup costs over a much larger market.
Compare to starting in Ireland and then hitting the UK, France, Germany, Poland etc. Each of those countries will incur startup costs but the market size is smaller so you'll make less profit (all other things being equal).
Are US companies selling only in US market? Why can't EU/UK startups address global markets?