I don't think you need integer encoding to process fixed lengths. They do it just fine at the word level for codons. You would need a specific mechanic processors for each different schema length pattern though.
I think bit flips have no effect on the appropriateness of either fixed length or null termed. But omissions and comissions are probably why anything fixed length doesn't work.
Which is closer to the storage mechanism of excel (XML), and not to it's visualization interface (tables).