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This afternoon 2025-09-10 I managed to get cellpose 4.06 running on my m4 mac with metal performance shaders [mps] for optimization in a mamba environment. When I tried to train a model tho, cellpose gave problems.

So I used claude4 to search for a solution. It said downgrade to 4.04. TLDR It worked. This whole process took like 30seconds, much faster than manually googling. Yes this is just one anecdote, but LLMs have sped my workflow up a bit.



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