Place modifiers on the thumb keys or - if you don't have any of those - use home row mods!
My ranking of measures from most effective to least effective:
1) Do everything you can to minimize workload of weak fingers (pinky & ring fingers). Just flipping control and caps lock is often not enough.
2) Split keyboard; halves roughly shoulder-width apart. Optimize for straight wrists both at rest and "in action". This usually results in zero tilting or slightly negative tilting.
My ranking of measures from most effective to least effective:
1) Do everything you can to minimize workload of weak fingers (pinky & ring fingers). Just flipping control and caps lock is often not enough.
2) Split keyboard; halves roughly shoulder-width apart. Optimize for straight wrists both at rest and "in action". This usually results in zero tilting or slightly negative tilting.
3) Concave designs.
4) Tenting.