FWIW I tried the Truly Ergonomic Keyboard, which is similar to the Kinesis in that it has the keys in straight columns, and I found no discernible benefit. In fact, I ended up going back to my MS Natural 4000 and returning the TEK because even after 60 days I couldn't get used to the layout (it's nice that they let you do that though!). I may have to try the Kinesis though, the curve seems better. TEK looked nice in theory but the flat style didn't really work for me.